Drug Over-the-Counter (OTC)
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Pharmacist's Guide

Table of Contents

Top Over-the-Counter (OTC) Drugs

OTC drugs are medications that are safe and effective for use by the general public without seeking treatment by a health professional. These drugs are usually located on shelves in pharmacies, grocery stores, and even in gas stations. OTC medicines treat a variety symptoms due to illness including pain, coughs and colds, diarrhea, heartburn, constipation, acne, and others.

Over-the-counter medications can still carry a risk, even though they do not require a prescription. There is the possibility of side effects, drug interactions, or harm due to excessive doses. Consumers should read the “Drug Facts” label that is found on all OTC products. All patients should consult with their doctor, pharmacist or other health care provider if they have additional questions concerning OTC drug use. Pregnant women should speak with their doctor before taking any medication, vitamin, or herbal supplement, even if it's an OTC product.

No Generic Name Trade Name Drug Use
1 Docosanol Abreva® Cold sore medication
2 Ibuprofen and pseudoephedrine HCl Advil Cold & Sinus® Allergy and cold relief
3 Ibuprofen Advil® Analgesic
4 Oxymetazoline HCl Afrin® Nasal decongestant
5 Naproxen sodium Aleve® Analgesic
6 Orlistat alli® Weight management
7 Benzocaine, phenol Anbesol® Oral cavity analgesic
8 Phenazopyridine hydrochloride Azo Standard® UTI analgesic
9 Acetylsalicylic acid (ASA, aspirin), diphenhydramine, caffeine, calcium, phytosterols Bayer® Aspirin Analgesic
10 Diphenhydramine HCl, phenylephrine HCl Benadryl® Oral Allergy and cold relief
11 Diphenhydramine HCl, zinc acetate or camphor Benadryl® Topical Topical antipruritic
12 Methyl salicylate, menthol, and camphor BENGAY® Topical analgesic
13 Meclizine hydrochloride, cyclizine hydrochloride Bonine® Motion sickness medication
14 Acetylsalicylic acid (ASA, aspirin) with buffers Bufferin® Analgesic
15 Capsaicin Capzasin-P Topical analgesic
16 Menthol, camphor, alum, salicylic acid Carmex® Lip Balm Cold sore medication
17 Benzocaine, menthol, dextromethorphan Cepacol® Oral cavity analgesic
18 Benzocaine and menthol or phenol Chloraseptic® Oral cavity analgesic
19 Calcium citrate Citracal® Essential mineral
20 Loratadine and pseudoephedrine sulfate Claritin-D® Allergy and cold relief
21 Loratadine Claritin® Allergy and cold relief
22 Docusate sodium Colace® Stool softener
23 Zincum gluconicum COLD-EEZE® Cold relief
24 Salicylic acid Compound W® Keratolytic
25 Hydrocortisone Cortaid® Topical antipruritic
26 Acetaminophen, dextromethorphan HBr, phenylephrine HCl DayQuil® Allergy and cold relief
27 Carbamide peroxide solution Debrox® Ear wax removal aid
28 Dextromethorphan polistirex Delsym® Cough suppressant
29 Zinc oxide Desitin® Skin protectant
30 Brompheniramine maleate, phenylephrine hydrochloride, dextromethorphan hydrobromide, loratadine Dimetapp® Allergy and cold relief
31 Dimenhydrinate or meclizine HCl Dramamine® Motion sickness medication
32 Bisacodyl Dulcolax® Laxative
33 Human chorionic gonadotropin (HCG) e.p.t.® Pregnancy test
34 Acetylsalicylic acid (aspirin, ASA) Ecotrin Analgesic
35 Phosphorated carbohydrates Emetrol® Antiemetic
36 Soy, black cohosh Estroven® Menopause support
37 Eucerin® Skin moisturizer
38 Acetaminophen, aspirin, caffeine, diphenhydramine citrate Excedrin® & Excedrin® PM Analgesic laxative
39 Polycarbophil calcium FiberCon®
40 First Response® Ovulation Test Ovulation test
41 Undecylenic acid Fungi-Nail® Antifungal, topical
42 Simethicone, calcium carbonate Gas-X® Antiflatulent
43 Menthol or pectin Halls® Cough Drops Antitussive
44 Loperamide HCl Imodium® A-D Antidiarrheal
45 Ammonium lactate, urea, salicylic acid Kerasal® Foot Cream Skin moisturizer
46 Lactase enzyme Lactaid® Digestive aid
47 Terbinafine hydrochloride or tolnaftate Lamisil® AT Antifungal
48 Clotrimazole or miconazole nitrate Lotrimin AF® Antifungal, topical
49 Aluminum hydroxide, magnesium hydroxide, calcium carbonate, simethicone Maalox® & Maalox® Max Antacid
50 Psyllium hydrophilic mucilloid Metamucil® Laxative
51 Pamabrom, pyrilamine maleate, acetaminophen, caffeine, ibuprofen, naproxen sodium, diphenhydramine Midol® Products Analgesic
52 Polyethylene glycol 3350, NF Miralaxª Laxative
53 Miconazole nitrate, tioconazole Monistat® Vaginal Vaginal antifungal
54 Ibuprofen Motrin® IB Analgesic
55 Guaifenesin, pseudoephedrine HCl, and dextromethorphan HBr Mucinex® (Adult) Expectorant
56 Aluminum hydroxide, magnesium (hydroxide and carbonate), calcium carbonate, simethicone Mylanta® Antacid
57 Simethicone Mylicon® Drops Antiflatulent
58 Pheniramine maleate, naphazoline HCl Naphcon® A Ophthalmic anti-allergy
59 Cromolyn sodium Nasalcrom® Allergy and cold relief
60 Polymyxin B sulfate, neomycin, bacitracin, pramoxine HCl Neosporin® Topical anti-infective
61 Nicotine transdermal Nicoderm® CQ® Smoking cessation aid
62 Nicotine polacrilex Nicorette® Smoking cessation aid
63 Permethrin Nix® Pediculicide
64 Ketoconazole Nizoral® AD Shampoo Antifungal, topical
65 Caffeine NoDoz® Analeptic
66 Chlorpheniramine maleate (CPH), dextromethorphan HBr (DXT), acetaminophen (APAP), doxylamine, succinate phenylephrine (PE) NyQuil® Cough and cold relief
67 Sodium chloride Ocean® Nasal Nasal decongestant
68 Benzocaine Orabase® Oral cavity analgesic
69 Benzocaine Orajel® Oral cavity anesthetic
70 Glucose oxidase, lactoperoxidase, lysozyme OralBalance® Oral moisturizer
71 Calcium carbonate Os-Cal® Essential mineral
72 Famotidine Pepcid-AC® Acid reducer
73 Famotidine, calcium carbonate, magnesium hydroxide/td> Pepcid® Complete Acid reducer
74 Bismuth subsalicylate Pepto Bismol® Antidiarrheal
75 Docusate sodium and senna Peri-Colace® Stool softener plus laxative
76 Magnesium hydroxide Phillips’ MOM Laxative/antacid
77 Pyrantel pamoate Pin-X® Anthelmintic
78 Shark liver oil, petrolatum, mineral oil, phenylephrine HCl Preparation H® Products Hemorrhoidal agent
79 Lansoprazole Prevacid® 24 Hour Acid reducer
80 Omeprazole magnesium Prilosec® OTC Acid reducer
81 Epinephrine, ephedrine, guaifenesin Primatene® Bronchodilator
82 Pyrethrins RID® Pediculicide
83 Guaifenesin (GUA), dextromethorphan (DXT), chlorpheniramine, diphenhydramine, acetaminophen (APAP) Robitussin® (Adult) Cough relief
84 Minoxidil Rogaine® Hair growth stimulant
85 Synthetic saliva Salivart® Saliva substitute
86 Standardized senna concentrate with or without docusate Senokot® Laxative
87 Chamomilla, mercurius solubilis, and sulphur Similasan Earache Relief® Earache relief
88 Magnesium chloride and calcium Slow-Mag® Essential mineral
89 Pseudoephedrine HCl (PSE), phenylephrine (PE), dextromethorphan HBr (DXT), acetaminophen (APAP), chlorpheniramine HCl (CPH), guaifenesin (GUA), Diphenhydramine Sudafed® Allergy and cold relief
90 Polyethylene glycol 400, propylene glycol Systane® Artificial tears
91 Hydroxypropyl methylcellulose, dextran 70, white petrolatum, mineral oil Tears Naturale® Artificial tears
92 Calcium carbonate TUMS® Antacid
93 Acetaminophen (APAP) Tylenol® Analgesic
94 Pseudoephedrine HCl (PSE), chlorpheniramine maleate (CPH), acetaminophen (APAP), guaifenesin, Doxylamine succinate, diphenhydramine Tylenol® Allergy and Sinus Allergy and cold relief
95 Pseudoephedrine HCl (PSE), chlorpheniramine maleate (CPH), dextromethorphan HBr (DXT), acetaminophen (APAP), doxylamine succinate Tylenol® Cold (Adult) Allergy and cold relief
96 Acetaminophen and diphenhydamine HCl Tylenol® PM Analgesic/sleep aid
97 Doxylamine succinate or diphenhydramine HCl Unisom® Sleeping aid
98 Tetrahydrozoline HCl, oxymetazoline HCl, naphazoline HCl, pheniramine maleate, ketotifen Visine® Ophthalmic vasoconstrictor
99 Ketotifen fumarate Zaditor® Ophthalmic anti-allergy
100 Ranitidine hydrochloride Zantac OTC Acid reducer
101 Zincum gluconicum and zincum aceticum Zicam® Cold Remedy Cold relief
102 Benzyl alcohol and benzocaine Zilactin® Cold sore medication
103 Cetirizine hydrochloride with pseudoephedrine hydrochloride Zyrtec-D® Antiallergy agent
104 Cetirizine hydrochloride Zyrtec® Antiallergy agent
No Generic Name Trade Name Drug Use

*Adapted from SFI Medical Publishing, Copyright 2011

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